The letter was sent in response to reports that the administration is prohibiting the use of well-defined technical terms such as “sexual and reproductive health,” “comprehensive sexuality education,” and other terms relating to sex, sexuality, and gender. This unprecedented proposal undermines nearly 25 years of global consensus and endangers decades of progress on global health. The organizations call on Pompeo to reverse and prevent any guidance or policy that prohibits free speech or weakens commitments to global health.